British families tell how their children have suffered tell-tale symptoms of 'inflammatory syndrome' linked to COVID-19 as officials investigate mysterious spike in number of youngsters being admitted to intensive care with serious condition (22 Pics)

More 'petrified' parents have come forward after their children were struck down with tell-tale signs of a mysterious coronavirus-linked inflammatory syndrome that has hospitalised at least 20 youngsters and left a dozen fighting for their lives.

An alert was issued by NHS bosses on Tuesday warning GPs there had been a surge in youngsters needing intensive care after falling seriously unwell with the illness which causes a fatal immune overreaction.

Health Secretary Matt Hancock said he was 'very worried' by the mystery syndrome which experts think is caused by coronavirus infection. The illness appears to be similar to Kawasaki disease - which causes blood vessels to become inflamed, and toxic shock syndrome - an overreaction by the immune system which causes the body to attack its own organs.    

Six British families revealed their children were struck down with symptoms synonymous with the serious condition - some of whom were never tested for COVID-19, leaving them in the dark about whether their illness was linked to the virus.

Gemma Brown, from Droitwich Spa, Worcestershire, told MailOnline her two-year-old son Bertie was admitted to hospital last month on his second birthday when his temperature soared over 40C (104F) and his blotchy rash began to turn black. 

Mrs Brown says she is certain her boy had the vicious virus but has no way of knowing because he was denied a test and diagnosed with the rare Kawasaki disease.

Melanie Cook, 38, from Gypsyville, Hull, revealed her one-year-old son George was infected with coronavirus when he was struck down with mystery symptoms in mid-March. 

She said she was '110 per cent sure' her son's red eyes, violent vomiting and fatigue was COVID-19-related, but claims her son was diagnosed with conjunctivitis and denied a swab. 

Parents Sabrina and Steve Legge, from Bath, Somerset, have been left petrified that sons Dylan, 16, and Colston, 14, have the inflammatory syndrome after suffering from sickness, blisters on their tongues, diarrhoea and stabbing chest pains last week. The family claim their GP has refused to test the teens for coronavirus. 

A mother from Lancashire, who does not wish to be named, shared shocking images of her two-year-old daughter with blotchy purple rashes across her entire body. The parent said she was waiting on coronavirus test results with bated breath.

And Lewis Greig, 13, from Aberdeen, was finally diagnosed with the lethal virus after becoming so ill he needed to be hooked up to a ventilator. The teenager initially was struck down with inflammatory symptoms including bloodshot eyes and measles-like rashes.

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A mother from Lancashire, who does not wish to be named, shared shocking images of her two-year-old daughter with blotchy purple rashes across her entire body

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Bertie Brown was admitted to Worcestershire Royal hospital last month on his second birthday after developing a fever and rash across his body

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Melanie Cook, 38, from Gypsyville, Hull, believes her one-year-old son George was struck down with the mystery disease in mid-March after suffering red, puffy eyes (shown), 'violent vomiting' and fatigue.

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Lewis Greig, from Torry, Aberdeen, has been on a ventilator at the Royal Hospital for Children, Glasgow, after he suddenly became unwell last week with a high temperature (pictured: Lewis, left, and the rash which appeared on his hand, right)

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Parents Sabrina and Steve Legge, from Bath, Somerset, have been left petrified that sons Colston (left), 14, and Dylan (right), 16,have the inflammatory syndrome after suffering from sickness, blisters on their tongues, diarrhoea and stabbing chest pains last week

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The condition is a form of toxic shock syndrome which causes the body's immune system to attack its own organs

Lewis Greig was not thought to have the virus because he did not have the usual dry cough but he is now on an intensive care ward at the Royal Hospital for Children in Glasgow.

Although Lewis has not been diagnosed with this toxic shock syndrome, medics have been warned to mindful of inflammatory symptoms such as his which could be linked to the coronavirus.  

Lewis's mother Karen Simpson said the teenager had suffered from vomiting, rashes and red swollen eyes. He was rushed to hospital in Aberdeen before being transferred to an intensive care unit in Glasgow, where he tested positive for coronavirus. 

Lewis is in a critical but stable condition and is showing signs of improvement, although his family must wear protective equipment while visiting.

Ms Simpson spoke about Lewis's ordeal to warn parents that children with COVID-19 can show different symptoms to adults.

Ms Simpson, who is currently staying in a Glasgow hotel to be close to her son, with Lewis's father Wayne, 47, said: 'It all started last Saturday when we discovered he had a temperature. It was really high - about 40.5 degrees.

'At first we didn't think it was anything too major. We assumed he had a bug and that it would pass.

'On the Sunday though, things weren't any better and Lewis started to get progressively worse as the week went on.

'He started being sick, had a sore head and was really tired. We'd already been on the phone to the COVID-19 hub on 111 and they said to make sure he was drinking - if they needed to admit him they would.

'By Thursday, he had developed a measles-like rash on his hands and his eyes went deep red and bloodshot.

'On Friday morning, he woke up in a bad way. We phoned the doctor, who had a quick look at him and they phoned the sick kids' hospital.

'We took him up straight away, and when we got there, he couldn't walk from the car into the building.'

Within hours of being taken to hospital, Lochside Academy pupil Lewis had been put on a ventilator to help him breathe.

And in the early hours of Saturday, he was transferred to Glasgow by ambulance.

Ms Simpson said: 'I have never seen anything like it before. It was so scary. The first few tests they did came back negative for COVID-19. But then they did another one and that came back positive on Sunday night.'

Ms Simpson now wants to make other parents aware of tell-tale signs which may show children are suffering from the virus.

She said: 'I want to help other parents understand how to spot it. They might show some really strange symptoms which aren't fitting with the normal coronavirus symptoms. Make sure you get them checked and keep pushing to have them tested.

'One of the doctors said to us children don't present with a dry cough like adults do. In children, there's an inflammatory reaction which makes it look like an autoimmune disease.'

Lewis, who is a brother to Nathan, Sam, Abby, Jorja and Eli, is now showing small signs of progress - and his family are determined to help him pull through.

Ms Simpson said: 'Lewis is now making small steady steps towards getting better, although he is still having to have quite a lot of medication and is still on a ventilator.

'He's able to move now and knows when we go into his room, although we can't have very much contact with him and need to wear PPE.

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His temperature soared over 40C (104F) and the blotchy rash spread across his body and began to turn black. Doctors were initially baffled but a senior consultant eventually diagnosed the boy with the rare Kawasaki disease

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His mother Gemma (pictured with Bertie and is older brother George, 14) believes his symptoms were a complication of the coronavirus. But Bertie (right) was not given a COVID-19 test, leaving both medics and his family in the dark about a possible link

'But he is showing some positive signs and he is definitely in the right place. He will get through this because he is a fighter.'

Gemma Brown, 38, told MailOnline that her son, Bertie, was admitted to Worcestershire Royal hospital last month on his second birthday, when his temperature soared over 40C (104F) and his blotchy rash began to turn black.

Doctors were initially baffled but a senior consultant eventually diagnosed the boy with the rare Kawasaki disease, a form of toxic shock syndrome which causes the body's immune system to attack its own organs.

But Bertie was not given a COVID-19 test, leaving both medics and his family in the dark about a possible link between Kawasaki disease and coronavirus.

'I don't know how the Government is going to prove there's a link if they're not testing patients,' the mother-of-two from Droitwich Spa, Worcestershire, said.

'I asked for him to be tested, as I had a gut feeling that there was a connection between covid and Kawasaki. Both attack your immune system and the whole family had been poorly with Covid symptoms before Bertie fell ill.

'I was adamant that there was a link and was begging for a test, but they just told me that there was no need to test the under-fives.'

The boy was given an immunoglobin transfusion and was in hospital for five days. 'It was horrific seeing him like that,' Mrs Brown said.

'He didn't have any respiratory problems but he was put in a ward on his own and he was easily the most poorly child in the hospital.

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Melanie Cook, 38, of Gypsyville, Hull, believes her 21-month-old son George showed signs of the ailment in mid-March

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George was diagnosed with conjunctivitis, cellulitis and scarlet fever during his five-week illness (in hospital, left), but having read about the new condition's associated symptoms, Mrs Cook is convinced her son had the mystery disease (right, his arm breaks out in a rash)

'His rash had started out being itchy, but it quickly put him in agony. His temperature was dangerously high and they were monitoring him round the clock.'

Bertie, who was born very prematurely weighing only 1.5lb, has always had a weak immune system, making him susceptible to viruses.

'Thank God he is OK now and has come home, though he's still on Aspirin to prevent his blood clotting,' his mother said.

'He's much better in himself. But the fact is that we just don't know what's been going on as he wasn't tested for coronavirus.'

Melanie Cook, 38, of Gypsyville, Hull, believes her 21-month-old son George showed signs of the ailment in mid-March. 

George was diagnosed with conjunctivitis, cellulitis and scarlet fever during his five-week illness, but having read about the new condition's associated symptoms, Mrs Cook is convinced her son had the mystery disease. 

She said: 'I'm not saying it's anyone's fault I just want to raise awareness about the symptoms and let people know that this is around because I 110% believe that George definitely had this.

'Now, seeing the cases of children having this and the symptoms they've had - they're giving this four week structure now saying about the red eyes, the sore throat, the rash and all these red patches and that's what he had.

'What I'm hearing them describe is exactly how it was happening.'

After an episode of 'violent vomiting', lethargy and redness around the eyes George was diagnosed on March 17 as having conjunctivitis by his GP and was given penicillin.

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Parents Sabrina and Steve Legge, from Bath, Somerset, have been left petrified that sons Dylan (left), 16, and Colston (right), 14, have the inflammatory syndrome. The family claim their GP has refused to test the teens for coronavirus

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Colstons tongue has developed blisters on either side after coming down with mysterious symptoms of the virus on Sunday

On Friday, March 20, Mrs Cook noticed red patches on her son's skin. She said: 'We were sat having tea, he had a jumper on and I took it off and he had these red patches on him just like the ones that we are now being told are symptoms but obviously at the time that wasn't linked to anything like that.

'All we knew as the symptoms of Covid were the cough and the temperature. So he had these red patches on the back of his legs and feet and hand and arms. My husband took him straight to the doctor's and came back with more antibiotics and said the doctor said he had cellulitis. We thought 'gosh he's just got over conjunctivitis and now this.'

By March 26, George had almost finished his course of antibiotics but was still ill. Mrs Cook said: 'He had developed a cough, the redness had turned into a rash and his breathing was bad.'

After another check-up George was diagnosed with scarlet fever. But things came to a head on the night of March 19.

Mrs Cook explained: 'He started vomiting, his temperature was really high, and his breathing was really bad. His rib cage was going in and out. He was asleep on me but he started convulsing and this really panicked me.

George was rushed in to hospital where medical staff stabilised his temperature before sending him home where he eventually recovered.

Mrs Cook said: 'We got put into a room and they gave him different shots to get his temperature down and checking his stats and everything like that.

'After four weeks I was at the end of my tether with it, pouring my heart out after all the things he'd been given and all these different shots.

'They told me they thought it was scarlet fever still because of his spots on his throat and the rashes. From the beginning of March it was maybe five weeks of him being ill until he finally got better.'

Although George has not been tested for Covid-19, Mrs Cook remains convinced that her son has suffered with the suspected coronavirus-related illness.

Sabrina and Steve Legge, from Bath, Somerset, have been left petrified for the health of sons Dylan, 16, and Colston, 14, who they believe have both shown symptoms of the inflammatory disease.  

Mother Sabrina and stepdad Steve claim they initially raised concerns with their GP at Combe Down Surgery, last Friday after Dylan had been ill for 10 days, but were advised to call back on Monday if the symptoms persisted.

But following fresh warnings from Matt Hancock that the new strain could be fatal, Sabrina, 42, and Steve, 47, were left even more concerned when Colston, who has autism, fell ill with the same symptoms on Sunday.

And the pair were left furious after they claim they called their GP back on Monday with concerns about both sons to allegedly be told 'it doesn't matter what Matt Hancock says - we don't hand out tests willy-nilly'.

The terrified parents are now begging medics to test their sons before it is too late. Radiology assistant and mother-of-three Sabrina said: 'Dylan has been in so much pain he couldn't sleep, he's been in more pain than when he had appendicitis two years ago - I've never seen him like this.

'When you hear Matt Hancock saying about these new findings and you get straight onto the GP the next day only to be fobbed off, it's just really worrying.

'We called NHS 111 and they said they were 90 per cent sure it was this new inflammatory disease linked to Covid-19 as well, but the only thing they can do is refer us to our GP who would need to then refer the boys to be tested and treated.

'It really does scare you as a parent, you just worry what's going to happen to them.' The family have been self-isolating together at their home with Sabrina's three children, Chloe, 17, Dylan, and Colston and Steve's daughter, Jessica, nine, for the last six weeks. 

After initially starting with vomiting and diarrhoea, Dylan's condition worsened to include constant stomach cramps and stabbing pains in chest that were so agonising he couldn't sleep or manage a meal.

Now Colston has started with the same sickness symptoms that his brother had, and the couple fear he will follow Dylan's pattern and develop agonising chest and stomach pains.

Property maintenance business owner, Steve, has branded the alleged decision by the GP to not test the boys for Covid-19 as 'disgusting' after already losing a loved-one to the pandemic.

He said: 'I'm absolutely furious and I think it's disgusting. I understand that the tests are very short but on one hand you have the Health Secretary telling people that children with these symptoms need to be referred as a matter of urgency, and then when we call the GP they refuse to see them or do anything.

'Dylan's had severe chest pains and stomach cramps, he's needed to go to the toilet every five minutes, he's been really ill.

'And now Colston is showing the same symptoms that Dylan had when this first started, he's got blisters on his tongue and bloodshot eyes and he's started vomiting.

'The GP basically told us that 'it doesn't matter what Matt Hancock says, we don't give tests out willy-nilly'.

'I've already lived through losing a loved one to Covid-19, we won't sit and watch it take one of our kids.'

A spokesperson for Combe Down Surgery said: 'While we are unable to comment on the healthcare of individual patients, we would like to reiterate the national guidance that any person with coronavirus-like symptoms should self-isolate for at least seven days, and to contact their GP should these symptoms persist for longer than a week.

'In most cases, children seem to be less susceptible to the effects of coronavirus than adults, however we would encourage any parent who has a child suffering from an urgent or pressing health concern, such as chest pain and a persistent high temperature, to seek help by calling NHS 111 or - in the most serious cases - 999.'

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The UK's total number of coronavirus deaths and infections per day

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The UK is still tracking on the same kind of course as outbreaks in France, Italy and Spain - although the figures are not exactly comparable

NHS doctors have been warned to look out for severe reactions in children - including symptoms like Bertie's. 

An urgent alert issued by NHS England said there was a 'growing concern' a COVID-19-related inflammatory syndrome was emerging, a rare form of toxic shock which is said to be similar to Kawasaki disease.

Doctors were yesterday issued an alert about a sharp rise in the number of infants being admitted to intensive care across the UK with the 'inflammatory syndrome' over the past three weeks. Most of the children affected already have Kawasaki disease, NHS sources said.

Health chiefs today insisted they are 'unaware' of any deaths in British children from the inflammatory syndrome - despite Matt Hancock admitting that 'some' youngsters have mysteriously died with no underlying conditions.  

Doctors were yesterday issued an alert about a sharp rise in the number of infants being admitted to intensive care across the UK with the Kawasaki-like disease. 

Officials have refused to say how many British children have been affected by the illness but up to 20 have fallen critically unwell, according to reports. One child needed to be put on a form of life support after their heart and lungs began to fail. The majority of the patients are thought to be under the age of five. 

The illness appears to be similar to Kawasaki disease - which causes blood vessels to become inflamed, and toxic shock syndrome - an overreaction by the immune system which causes the body to attack its own organs.  

The Health Secretary was quizzed on LBC about the inflammatory syndrome and admitted he was 'very worried' by the mysterious complication. He was also asked about how many children had died from coronavirus. 

Mr Hancock originally said all the deceased youngsters had 'significant underlying health conditions' but then backtracked immediately after host Nick Ferrari questioned him about the new inflammatory illness that had prompted the national alert. Mr Hancock then admitted 'some' children with no health woes had succumbed to COVID-19. 

The Department of Health today insisted that Mr Hancock was not referring to children who have died from the inflammatory syndrome potentially linked to the disease - and was discussing COVID-19 deaths in general.   

Officials have yet to offer any clarity on exactly what the symptoms are, despite pleas from paediatricians to paint a clearer picture so they can look out for them. Kawasaki disease and toxic shock syndrome, combined, cause harmful internal swelling, fever and breathing problems - all hallmark signs of COVID-19. 

Officials told the PA news agency fewer than 20 children in England have been admitted to hospital with the mysterious syndrome. 

Doctors have compared it to toxic shock syndrome and Kawasaki disease which, combined, cause harmful internal swelling, fever and breathing problems - all signs of coronavirus.

But some of the children needing intensive care have tested negative for COVID-19, further complicating the diagnosis and raising questions that another pathogen could be behind the condition.  

Officials have yet to offer any clarity on what the symptoms are, despite pleas from paediatricians to paint a clearer picture so they can look out for them.

It is not clear how many children have had the inflammatory syndrome, nor how many have died with it. It is also unclear how old the children have been.  

However, most of the children affected by the inflammatory syndrome already have Kawasaki disease, an NHS source told The Guardian. 

Kawasaki disease is a condition that causes inflammation in the walls of the blood vessels and affects mostly children under five years old. 

There are roughly eight cases for every 100,000 children in the UK and statistics show it is fatal in three per cent of cases that go untreated.

The new COVID-19-linked cases are occurring when someone with Kawasaki disease contracts the virus and it produces complications, the source told the newspaper. 

Children are not thought to be badly affected by COVID-19 - very few youngsters have died around the world since the pandemic began in December. 

Their apparent resilience to the disease has baffled doctors for weeks because they are often 'super-spreaders' of viral illnesses such as flu.

But children being seen with this syndrome often suffer from stomach pain, heart inflammation and 'gastrointestinal symptoms' - which could include vomiting and diarrhoea.

NHS medical director Professor Stephen today urged parents who are worried about a child who is sick and not recovering to seek medical help.

Chief medical officer Professor Chris Whitty said yesterday is 'entirely plausible' this spike is linked to the COVID-19 outbreak. 

Speaking at No 10's press briefing yesterday, he added: 'Because we know that in adults who of course have much more disease than children do, big problems are caused by an inflammatory process and this looks rather like an inflammatory process, a rather different one.

'Therefore, given that we have got a new presentation of this at a time with a new disease, the possibility - it is not a definite, we need to look for other causes as well - but the possibility that there is a link is certainly plausible.'